Scientists at The Institute of Cancer Research (ICR), London, and the Hubrecht Institute-KNAW in the Netherlands have identified a new genetic cause of a childhood kidney cancer called Wilms tumour, revealing insights into how loss of control of chromosome number can lead to cancer.

Their study will help parents understand why their children have developed cancer and provide information about the risk of cancer for other children.

It has also provided valuable information about the fundamental biology of cancer, by shedding new light on how the disease may be linked to disruptions to the process for distributing chromosomes between cells when cells divide.

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