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A recent study to be published in Clinical and Experimental Medicine next month investigates the role of microRNAs (miRNAs) in the development of renal cell carcinoma (RCC) and the levels of miRNA-15a in RCC tumours.
The investigators showed that increased miRNA-15a was associated with indicators of poor prognosis, such as high Fuhrman grade, the presence of necrosis, and spread to lymph nodes. Furthermore, these patients had shorter survival.
These findings suggest that miRNA-15a has promising potential as a prognostic biomarker for RCC.