Collecting duct carcinoma of the kidney is a very aggressive form of kidney cancer. It is often diagnosed late when the cancer has already spread. Early surgical treatment is valuable for these patients.
In this study, the researchers looked at data collected over 19 years from two hospitals. They evaluated the appearance of the tumours on scans and various characteristics of collecting duct carcinoma of the kidney.
Low back pain, blood in the urine, and fatigue were the most common symptoms among the patients. In total, 32% of the patients had metastases when they first went to see their doctor, and in 17.6% of patients their tumour had grown in the blood vessels surrounding the kidney (tumour thrombus).
61 patients had their tumour removed by surgery and the average size of the tumour was 6.5 cm. Some patients were treated with immunotherapies. Half of these patients had complete or partial response to treatment or stable disease. Average overall survival time was 2 years.
Immunotherapy treatment gives hope to patients with collecting duct carcinoma of the kidney.