A recent review and meta-analysis of 19 observational studies involving nearly 2 million patients with end-stage renal disease (ESRD) reported that these patients are at increased risk for kidney and urothelial cancers. The study was reported in the journal Nephrology.
ESRD is associated with 6-fold increased risk for kidney cancer and 4.4-fold increased risk of urothelial cancers compared to people without ESRD. Urothelial cancers included cancer of the bladder, ureters, and renal pelvis. The pooled estimated incidence of kidney cancer and urothelial cancers in ESRD patients were 0.3% and 0.5%, respectively, according to researchers at the Mayo Clinic in Rochester, Minnesota, and Bassett Medical Center in Cooperstown, New York.