Researchers from the IRCCS San Raffaele Scientific Institute in Milan, Italy, examined trends in the clinical characteristics of high-risk renal cell carcinoma (RCC) over a 25-year period.
Their findings, which were published in Anticancer Research this month, reported that patients are being diagnosed at an older age and with smaller tumours. Also, the number of patients without symptoms (asymptomatic) at diagnosis has increased, and the proportion of patients without metastases has increased by 15.3%.
As a result in the increasing number of small tumours being detected, partial nephrectomy surgery has increased by 23.3%, despite the high-risk cancer profile of the patients. The findings also show that the number of enlarged lymph nodes has remained stable over time.