The treatment of patients with intermediate- and poor-risk metastatic renal cell carcinoma (RCC) has been dramatically changed with the introduction of immune checkpoint inhibitors (immunotherapy) as a first-line of treatment after surgery. However, it is less clear whether immunotherapy benefits patients with favourable-risk disease in the same way. A debate between experts at the International Kidney Cancer Symposium in Miami this week highlights different approaches to the treatment of favourable-risk RCC, including tyrosine kinase inhibitors (VEGF inhibitors), combination immunotherapy and active surveillance.
Treatment of favourable-risk metastatic kidney cancer
20 Nov 2019
active surveillance
checkpoint inhibitors
favourable risk
immunotherapy
renal cell carcinoma
TKIs
VEGF inhibitors
Most used tags
renal cell carcinoma immunotherapy combination therapy checkpoint inhibitors Cancer nivolumab TKIs overall survival Opdivo sunitinib Sutent progression-free survival cabozantinib biomarkers NHS England Cabometyx ipilimumab pembrolizumab COVID-19 cancer survival axitinib VEGF inhibitors non-clear cell kidney cancer Inlyta coronavirus Yervoy risk factors Keytruda metastases adjuvant therapy biological markers papillary RCC targeted therapy everolimus Afinitor ASCO cancer outcomes first-line treatment NICE partial nephrectomyArchives
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