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A new study, published in the International Brazilian Journal of Urology, shows that higher circulating concentrations of 25-hydroxyvitamin D in the blood are associated with a lower risk of renal cell carcinoma (RCC).
The study, conducted in China, compared 135 newly diagnosed cases of RCC with 135 controls matched by age and sex. The investigators found that average plasma levels of 25-hydroxyvitamin D were significantly lower in people with RCC than in the control group. People with 25-hydroxyvitamin D plasma levels of 20–29.9 ng/mL and 30 ng/mL or higher had a significant 50% and 70% decreased risk odds of RCC respectively, and each 10 ng/mL increment in 25-hydroxyvitamin D was associated with a significant 13% decreased risk of RCC.